Dietary Pulmonary Hypertension

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Dietary pulmonary hypertension.

In 1967 Kay et al postulated that some cases of unexplained pulmonary hypertension might be due to the ingestion of drugs or other toxic substances.' This concept, later termed dietary pulmonary hypertension,23 was advanced following the observation that the oral administration to rats of the pyrrolizidine alkaloid monocrotaline produced severe pulmonary hypertension.' There are no reports of p...

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Dietary pulmonary hypertension.

• The regulation of the pulmonary circulation is inextricably linked to the role of the lungs in gas exchange. Accordingly, it is not surprising that hypoxia and acidosis predominate as stimuli for vasomotor activity or that their main effects are exerted locally on the pulmonary vascular tree. Although pulmonary vasomotor nerves do exist, they operate more to adjust the distensibility of capac...

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Thalassemia Associated Pulmonary Hypertension

Cardiac disease is the main cause of death in both forms of thalassemia; thalassemia major (TM) and thalassemia intermedia (TI). Pulmonary hypertension (PH) is one of the cardiopulmonary morbidities with high mortality that, if not treated, may trigger right-sided heart failure and premature death. PH is defined as a mean pulmonary artery pressure of ≥25 mmHg at rest or ≥30 mmHg during exercise...

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Evaluation of Pulmonary Hypertension In First Degree Relatives Of Patients With Primary Pulmonary Hypertension

Background: Pulmonary hypertension (PH) was defined for the first time in 1951 as primary pulmonary hypertension (PPH). Some studies emphasized on the role of genetics in the development of pulmonary hypertension in family members of affected patients. So, in this study we evaluated the prevalence of pulmonary hypertension in first degree family of patients with documented PPH. Methods: In thi...

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Background: Pulmonary Arterial Hypertension (PAH), a fatal orphan disease, is defined as increased mean Pulmonary Arterial Pressure (mPAP) above 25 mm/Hg, Pulmonary Capillary Wedge Pressure (PCWP) below 15 mm/Hg, and pulmonary vascular Resistance over 3 Wood Unit (WU). Although Pulmonary Hypertension (PH) is a relatively prevalent disease, the idiopathic form (iPAH) is a rare disease with a pre...

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ژورنال

عنوان ژورنال: Circulation Research

سال: 1974

ISSN: 0009-7330,1524-4571

DOI: 10.1161/01.res.35.5.657